<html><head></head><body><div class="ydp169feab7yahoo-style-wrap" style="font-family:Helvetica Neue, Helvetica, Arial, sans-serif;font-size:13px;"><div dir="ltr" data-setdir="false"><div><div style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px; text-align: center;"><div dir="ltr" data-setdir="false"><span class="ydp60f13700il">Neural</span> <span class="ydp60f13700il">Mechanisms</span> Online</div><div>(<a href="https://www.neuralmechanisms.org/" data-saferedirecturl="https://www.google.com/url?q=https://www.neuralmechanisms.org/&source=gmail&ust=1612514179083000&usg=AFQjCNFQMB0j7y47n9IgB5kzyhhWGcs7TQ" style="color: rgb(17, 85, 204); text-decoration-line: underline;" rel="nofollow" target="_blank">website</a>)</div></div><div style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px; text-align: center;"><b><br></b></div><div style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px; text-align: center;"><font size="2"><b style="color: rgb(255, 0, 0);">5 February<br></b></font></div><div style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px; text-align: center;"><b>Webinar</b><br></div><div style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px; text-align: center;"><span style="font-size: small;"><font color="#ff0000" style="background-color: inherit;"><b>h15-17</b> <b>Greenwhich Mean Time </b></font></span></div><div style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px; text-align: center;"><span style="font-size: small;">(</span><a href="https://www.timeanddate.com/worldclock/converter.html?iso=20210205T150000&p1=tz_gmt" data-saferedirecturl="https://www.google.com/url?q=https://www.timeanddate.com/worldclock/converter.html?iso%3D20210205T150000%26p1%3Dtz_gmt&source=gmail&ust=1612514179083000&usg=AFQjCNHFdOwxVizxu0ln5TMG5X1geipg9w" style="color: rgb(17, 85, 204); text-decoration-line: underline;" rel="nofollow" target="_blank"><i>check your local time here</i></a>)</div><div style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px; text-align: center;"><br></div><div style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px; text-align: center;"><table width="100%" cellspacing="0" cellpadding="3" border="0" style="font-family: Times New Roman;"><tbody><tr style="font-family: ciscosansttregular, Helvetica Neue, Helvetica, Arial, sans-serif; font-size: 14px;"><td valign="top" nowrap="" style="font-family: Roboto, RobotoDraft, Helvetica, Arial, sans-serif; margin: 0px;"></td><td valign="top" nowrap="" style="font-family: Roboto, RobotoDraft, Helvetica, Arial, sans-serif; margin: 0px;"><font size="2" face="arial, sans-serif"><a href="https://unito.webex.com/unito-en/onstage/g.php?MTID=e2fcf4655a4ec4ff37a396dec29e014e5" data-saferedirecturl="https://www.google.com/url?q=https://unito.webex.com/unito-en/onstage/g.php?MTID%3De2fcf4655a4ec4ff37a396dec29e014e5&source=gmail&ust=1612514179083000&usg=AFQjCNGnW6YRvHM7VIt7PzANrssIiRNqMw" style="color: rgb(17, 85, 204); text-decoration-line: underline;" rel="nofollow" target="_blank">https://unito.webex.com/unito-en/onstage/g.php?MTID=e2fcf4655a4ec4ff37a396dec29e014e5</a></font><br></td></tr></tbody></table></div><div style="color: rgb(0, 0, 0); font-family: Helvetica Neue, Helvetica, Arial, sans-serif; text-align: center;"><i style="font-family: arial, sans-serif; font-size: 12.8px;">the link will be activated 10 mins before the talk. </i></div><div style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px; text-align: center;"><br></div><div style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px; text-align: center;"><br></div><div style="color: rgb(0, 0, 0); font-family: Helvetica Neue, Helvetica, Arial, sans-serif; text-align: center;"><font size="4"><b><u>John BICKLE</u></b></font></div><div style="color: rgb(0, 0, 0); font-family: Helvetica Neue, Helvetica, Arial, sans-serif; text-align: center;"><font size="2" style="background-color: inherit;">(Mississippi State University &<br></font><font size="2" style="background-color: inherit;">University of Mississippi Medical Center</font><font size="2" style="background-color: inherit;">)</font><span style="font-family: arial, sans-serif; font-size: 12.8px;"></span></div><span style="color: rgb(0, 0, 0); font-family: arial, sans-serif; font-size: 12.8px;"><div dir="ltr"><br></div><div style="text-align: center;"><font size="4"><b><br></b></font></div><div style="text-align: center;"><font size="4"><b>Tinkering in the Lab<br></b></font></div><div style="text-align: center;"><br></div></span><div style="color: rgb(0, 0, 0); font-family: Helvetica Neue, Helvetica, Arial, sans-serif; font-size: 12.8px; text-align: center;"><div style="font-family: arial, sans-serif;"><span style="font-size: 12.8px;">The “science-in-practice” movement has brought wider philosophical attention to aspects of day-to-day science less closely tied to the issue of theory and its relationship to the world. And recent philosophy of neuroscience has contributed mightily to an emerging “philosophy of experiment.” But a focus on the development of research tools in wetlab sciences like neurobiology illustrates not just the dependence of theory on these tools, but a further dependence of these tools on atheoretical laboratory “tinkering.” Toward these ends of explicating laboratory “tinkering” as a part of scientific practice, and of further “putting theory in its place” in wetlab sciences, I focus here on the development of two neurobiology lab tools that revolutionized the field in the 20</span><sup>th</sup><span style="font-size: 12.8px;"> century: the metal microelectrode and the patch clamp. Both of these tools beautifully illustrate these two ends.</span></div></div></div><br></div><div><br></div><div class="ydp169feab7signature"><div><br></div><div><br></div><div><br></div></div></div></body></html>